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Skeletal muscle relaxants are a heterogeneous group of medications. As a class, they are structurally and pharmacologically diverse. Muscle relaxants are used to treat two different types of underlying conditions:
- spasticity from upper motor neuron syndromes
- muscular pain or spasms from peripheral musculoskeletal conditions
Although muscle relaxants have by convention been classified into one group, the Food and Drug Administration (FDA) has approved only a few medications in this class for treatment of spasticity. The remainder are approved for treatment of musculoskeletal conditions.
***** classified as skeletal muscle relaxants include:
baclofen (Lioresal), carisoprodol (Soma), chlorzoxazone (Paraflex), cyclobenzaprine (Flexeril), dantrolene (Dantrium), metaxalone (Skelaxin), methocarbamol (Robaxin), orphenadrine (Norflex), tizanidine (Zanaflex)
Muscle relaxants for treatment of musculoskeletal conditions
Muscle spasm is defined as a sudden involuntary contraction of one or more muscle groups and is usually an acute condition associated with muscle strain (partial tear of a muscle) or sprain (partial or complete rupture of a ligament). Common musculoskeletal conditions causing tenderness and muscle spasms include fibromyalgia, tension headaches, myofascial pain syndrome, and mechanical low back pain or neck pain. If muscle spasm is present in these conditions, it is related to local factors involving the affected muscle groups.
The skeletal muscle relaxants flexeril, carisoprodol, chlorzoxazone, cyclobenzaprine, metaxalone, methocarbamol, and orphenadrine are approved for treatment of musculoskeletal disorders. You can buy flexeril online at online pharmacies.
Clinical studies show, that cyclobenzaprine, carisoprodol, orphenadrine, and tizanidine are effective compared to placebo in patients with musculoskeletal conditions (primarily acute back or neck pain). Cyclobenzaprine has been evaluated in the most clinical trials and has consistently been found to be effective.
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January 30th, 2010 at 10:01 am
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